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FLT3-ITD, NPM1, and DNMT3A Gene Mutations and Risk Factors in Normal Karyotype Acute Myeloid Leukemia and Myelodysplastic Syndrome Patients in Upper Northern Thailand

OBJECTIVE: Approximately 40-45% of AML and MDS patients have a cytogenetically normal karyotype (CN-AML and CN-MDS). The frequency and types of gene mutations in these cases may differ among various populations. The objective of this study was to identify frequencies and types of FLT3-ITD, NPM1, and...

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Detalles Bibliográficos
Autores principales: Mevatee, Piyanan, Tantiworawit, Adisak, Traisathit, Patrinee, Puaninta, Chaniporn, Mevatee, Umnat, Angsuchawan, Sirinda, Bumroongkit, Kanokkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773788/
https://www.ncbi.nlm.nih.gov/pubmed/29172276
http://dx.doi.org/10.22034/APJCP.2017.18.11.3031