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Opioid‐induced inhibition of the human 5‐HT and noradrenaline transporters in vitro: link to clinical reports of serotonin syndrome

BACKGROUND AND PURPOSE: Opioids may inhibit the 5‐HT transporter (SERT) and the noradrenaline transporter (NET). NET inhibition may contribute to analgesia, and SERT inhibition or interactions with 5‐HT receptors may cause serotonergic toxicity. However, the effects of different opioids on the human...

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Detalles Bibliográficos
Autores principales:	Rickli, Anna, Liakoni, Evangelia, Hoener, Marius C, Liechti, Matthias E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773950/ https://www.ncbi.nlm.nih.gov/pubmed/29210063 http://dx.doi.org/10.1111/bph.14105

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