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Somatic evolutionary timings of driver mutations

BACKGROUND: A unified analysis of DNA sequences from hundreds of tumors concluded that the driver mutations primarily occur in the earliest stages of cancer formation, with relatively few driver mutation events detected in the late-arising subclones. However, emerging evidence from the sequencing of...

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Detalles Bibliográficos
Autores principales:	Gomez, Karen, Miura, Sayaka, Huuki, Louise A., Spell, Brianna S., Townsend, Jeffrey P., Kumar, Sudhir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774140/ https://www.ncbi.nlm.nih.gov/pubmed/29347918 http://dx.doi.org/10.1186/s12885-017-3977-y

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