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Characterization of Ca(V)1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and Ca(V)1.2 exon 33 expressions in human heart failure
Recently, we reported that homozygous deletion of alternative exon 33 of Ca(V)1.2 calcium channel in the mouse resulted in ventricular arrhythmias arising from increased Ca(V)1.2(Δ33) I(CaL) current density in the cardiomyocytes. We wondered whether heterozygous deletion of exon 33 might produce car...
Autores principales: | Wang, Juejin, Li, Guang, Yu, Dejie, Wong, Yuk Peng, Yong, Tan Fong, Liang, Mui Cheng, Liao, Ping, Foo, Roger, Hoppe, Uta C., Soong, Tuck Wah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774182/ https://www.ncbi.nlm.nih.gov/pubmed/28949795 http://dx.doi.org/10.1080/19336950.2017.1381805 |
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