Cargando…

Antimicrobial Studies Using the Therapeutic Tissue Cross-Linking Agent, Sodium Hydroxymethylglycinate: Implication for Treating Infectious Keratitis

PURPOSE: Our recent studies raise the possibility of using sodium hydroxymethylglycinate (SMG), for pharmacologic therapeutic tissue cross-linking (TXL) of the cornea. The present study was performed to evaluate the antimicrobial effects of SMG for potential use in treating infectious keratitis. MET...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rapuano, Patrick B., Scanameo, Alexandra H., Amponin, Daeryl E., Paulose, Sefy A., Zyablitskaya, Mariya, Takaoka, Anna, Suh, Leejee H., Nagasaki, Takayuki, Trokel, Stephen L., Paik, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774256/ https://www.ncbi.nlm.nih.gov/pubmed/29346493 http://dx.doi.org/10.1167/iovs.17-23111

Ejemplares similares

Ex vivo anti-microbial efficacy of various formaldehyde releasers against antibiotic resistant and antibiotic sensitive microorganisms involved in infectious keratitis
por: Amponin, Daeryl E., et al.
Publicado: (2020)

Development of a topical tissue cross-linking solution using sodium hydroxymethylglycinate (SMG): viscosity effect
por: Mehta, Jaya, et al.
Publicado: (2020)

Topical Corneal Cross-Linking Solution Delivered Via Corneal Reservoir in Dutch-Belted Rabbits
por: Zyablitskaya, Mariya, et al.
Publicado: (2020)

Evaluation of Therapeutic Tissue Crosslinking (TXL) for Myopia Using Second Harmonic Generation Signal Microscopy in Rabbit Sclera
por: Zyablitskaya, Mariya, et al.
Publicado: (2017)

An Evaluation of Lysyl Oxidase–Derived Cross-Linking in Keratoconus by Liquid Chromatography/Mass Spectrometry
por: Takaoka, Anna, et al.
Publicado: (2016)

Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies
por: Zhu, Hong, et al.
Publicado: (2017)

Designed Host Defense Peptides for the Treatment of Bacterial Keratitis
por: Clemens, L. Edward, et al.
Publicado: (2017)

The Role of SREC-Ⅰ in Innate Immunity to Aspergillus fumigatus Keratitis
por: Zhang, Ranran, et al.
Publicado: (2021)

A Central Role for Sympathetic Nerves in Herpes Stromal Keratitis in Mice
por: Yun, Hongmin, et al.
Publicado: (2016)

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis
por: Zhang, Bi Ning, et al.
Publicado: (2023)

The Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection
por: Li, Chenyu, et al.
Publicado: (2020)

Impact of implementation of polymerase chain reaction on diagnosis, treatment, and clinical course of Acanthamoeba keratitis
por: Roth, Mathias, et al.
Publicado: (2023)

Indoleamine 2,3-Dioxygenase Regulates Macrophage Recruitment, Polarization and Phagocytosis in Aspergillus Fumigatus Keratitis
por: Jiang, Nan, et al.
Publicado: (2020)

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study
por: Kim, Yu Jeong, et al.
Publicado: (2022)

Dupilumab-associated blepharoconjunctivitis
por: Paulose, Sefy A., et al.
Publicado: (2019)

ISG15 in Host Defense Against Candida albicans Infection in a Mouse Model of Fungal Keratitis
por: Dong, Chen, et al.
Publicado: (2017)

Innate and Adaptive Gene Single Nucleotide Polymorphisms Associated With Susceptibility of Severe Inflammatory Complications in Acanthamoeba Keratitis
por: Carnt, Nicole A., et al.
Publicado: (2021)

Prophylactic Knockdown of the miR-183/96/182 Cluster Ameliorates Pseudomonas aeruginosa–Induced Keratitis
por: McClellan, Sharon, et al.
Publicado: (2021)

Gallic Acid Ameliorates Aspergillus Fumigatus Keratitis Through Reducing Fungal Load and Suppressing the Inflammatory Response
por: Luan, Songying, et al.
Publicado: (2022)

Isorhamnetin Ameliorates Aspergillus fumigatus Keratitis by Reducing Fungal Load, Inhibiting Pattern-Recognition Receptors and Inflammatory Cytokines
por: Tian, Xue, et al.
Publicado: (2021)

Inhibition of miR-665-3p Enhances Autophagy and Alleviates Inflammation in Fusarium solani-Induced Keratitis
por: Guo, Qunqin, et al.
Publicado: (2021)

Baicalein Protects Against Aspergillus fumigatus Keratitis by Reducing Fungal Load and Inhibiting TSLP-Induced Inflammatory Response
por: Zhu, Yunan, et al.
Publicado: (2021)

Role of IL-36γ/IL-36R Signaling in Corneal Innate Defense Against Candida albicans Keratitis
por: Dai, Chenyang, et al.
Publicado: (2021)

METTL3 Attenuates Inflammation in Fusarium solani–Induced Keratitis via the PI3K/AKT Signaling Pathway
por: Huang, Liwei, et al.
Publicado: (2022)

CLEC-1 Acts as a Negative Regulator of Dectin-1 Induced Host Inflammatory Response Signature in Aspergillus fumigatus Keratitis
por: Zhu, Guoqiang, et al.
Publicado: (2021)

Perillaldehyde Ameliorates Aspergillus fumigatus Keratitis by Activating the Nrf2/HO-1 Signaling Pathway and Inhibiting Dectin-1-Mediated Inflammation
por: Fan, Yiqun, et al.
Publicado: (2020)

MiR-223-3p Regulates Autophagy and Inflammation by Targeting ATG16L1 in Fusarium solani–Induced Keratitis
por: Tang, Hanfeng, et al.
Publicado: (2022)

Bilateral Limbal Stem Cell Alterations in Patients With Unilateral Herpes Simplex Keratitis and Herpes Zoster Ophthalmicus as Shown by In Vivo Confocal Microscopy
por: Liu, Xintian, et al.
Publicado: (2021)

TSLP Produced by Aspergillus fumigatus-Stimulated DCs Promotes a Th17 Response Through the JAK/STAT Signaling Pathway in Fungal Keratitis
por: Han, Fang, et al.
Publicado: (2020)

Inhibition of the m6A Methyltransferase METTL3 Attenuates the Inflammatory Response in Fusarium solani-Induced Keratitis via the NF-κB Signaling Pathway
por: Tang, Hanfeng, et al.
Publicado: (2022)

IL-36α Exerts Proinflammatory Effects in Aspergillus fumigatus Keratitis of Mice Through the Pathway of IL-36α/IL-36R/NF-κB
por: Niu, Yawen, et al.
Publicado: (2021)

Corneal collagen crosslinking in patients treated with dextran versus isotonic hydroxypropyl methylcellulose (HPMC) riboflavin solution: a retrospective analysis
por: Rapuano, Patrick B., et al.
Publicado: (2018)

Outcomes of four-point suture fixated and two-point sutureless posterior chamber IOLs combined with pars plana vitrectomy
por: Zyablitskaya, Mariya, et al.
Publicado: (2022)

Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion
por: Luna, Carolina, et al.
Publicado: (2021)

Deep Convolutional Neural Networks Detect no Morphological Differences Between Culture-Positive and Culture-Negative Infectious Keratitis Images
por: Kogachi, Kaitlin, et al.
Publicado: (2023)

Assessment of Keratitis Severity Using Quantitative Image Analysis in an In Vivo Murine Model of Staphylococcus aureus Bacterial Keratitis
por: Meijome, Tomas E., et al.
Publicado: (2022)

Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells
por: Ali, Muhammad, et al.
Publicado: (2018)

Experimental Induction of Acute Acanthamoeba castellanii Keratitis in Cats
por: Ledbetter, Eric C., et al.
Publicado: (2023)

Effect of Penetrating Keratoplasty and Keratoprosthesis Implantation on the Posterior Segment of the Eye
por: Črnej, Alja, et al.
Publicado: (2016)

The effect of day-long mask wearing on non-invasive break-up time
por: Bilici, Serdar, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6lput4u0tk0g5lmhj3ut3mbdgm