Cargando…

Research of Mrr1, Cap1 and MDR1 in Candida albicans resistant to azole medications

The aim of the present study was to investigate the association between Mrr1, adenylyl cyclase-associated protein 1 (Cap1) and multi-drug resistance gene 1 (MDR1), and to assess the mutations in Mrr1 and Cap1 in azole-resistant Candida albicans strains. The study isolated 68 C. albicans strains from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Wenli, Yang, Jing, Yang, Lu, Li, Qing, Zhu, Xin, Xi, Zhiqin, Qiao, Zusha, Cen, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774345/ https://www.ncbi.nlm.nih.gov/pubmed/29434708 http://dx.doi.org/10.3892/etm.2017.5518

Ejemplares similares

The Transcription Factor Mrr1p Controls Expression of the MDR1 Efflux Pump and Mediates Multidrug Resistance in Candida albicans
por: Morschhäuser, Joachim, et al.
Publicado: (2007)

Cotreatment with Aspirin and Azole Drugs Increases Sensitivity of Candida albicans in vitro
por: Feng, Wenli, et al.
Publicado: (2021)

Transcriptional Response of Candida auris to the Mrr1 Inducers Methylglyoxal and Benomyl
por: Biermann, Amy R., et al.
Publicado: (2022)

The Transcription Factor Ndt80 Does Not Contribute to Mrr1-, Tac1-, and Upc2-Mediated Fluconazole Resistance in Candida albicans
por: Sasse, Christoph, et al.
Publicado: (2011)

Quinone derivatives isolated from the endolichenic fungus Phialocephala fortinii are Mdr1 modulators that combat azole resistance in Candida albicans
por: Xie, Fei, et al.
Publicado: (2016)

Balancing Positive and Negative Selection: In Vivo Evolution of Candida lusitaniae MRR1
por: Demers, Elora G., et al.
Publicado: (2021)

The effects of secreted aspartyl proteinase inhibitor ritonavir on azoles‐resistant strains of Candida albicans as well as regulatory role of SAP2 and ERG11
por: Feng, Wenli, et al.
Publicado: (2021)

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
por: Whaley, Sarah G., et al.
Publicado: (2017)

Screening of potential genes contributing to the macrocycle drug resistance of C. albicans via microarray analysis
por: Yang, Jing, et al.
Publicado: (2017)

Azole Compounds as Inhibitors of Candida albicans: QSAR Modelling
por: Gheidari, Davood, et al.
Publicado: (2021)

Chloroquine sensitizes biofilms of Candida albicans to antifungal azoles
por: Shinde, Ravikumar Bapurao, et al.
Publicado: (2013)

Candida albicans gains azole resistance by altering sphingolipid composition
por: Gao, Jiaxin, et al.
Publicado: (2018)

The Adr1 transcription factor directs regulation of the ergosterol pathway and azole resistance in Candida albicans
por: Shrivastava, Manjari, et al.
Publicado: (2023)

Reversal of Azole Resistance in Candida albicans by Human Neutrophil Peptide
por: Khan, Mohammad Imran, et al.
Publicado: (2023)

Effects of Hsp90 Inhibitor Ganetespib on Inhibition of Azole-Resistant Candida albicans
por: Yuan, Rui, et al.
Publicado: (2021)

Fructose Induces Fluconazole Resistance in Candida albicans through Activation of Mdr1 and Cdr1 Transporters
por: Suchodolski, Jakub, et al.
Publicado: (2021)

Corrigendum: Effects of Hsp90 Inhibitor Ganetespib on Inhibition of Azole-Resistant Candida albicans
por: Yuan, Rui, et al.
Publicado: (2021)

Author Correction: Candida albicans gains azole resistance by altering sphingolipid composition
por: Gao, Jiaxin, et al.
Publicado: (2019)

Azole Drugs Are Imported By Facilitated Diffusion in Candida albicans and Other Pathogenic Fungi
por: Mansfield, Bryce E., et al.
Publicado: (2010)

Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole
por: Kukurudz, Rebekah J, et al.
Publicado: (2022)

Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance
por: Keniya, Mikhail V., et al.
Publicado: (2015)

Candida albicans and Candida dubliniensis Show Different Trailing Effect Patterns When Exposed to Echinocandins and Azoles
por: Ayadi, Rania, et al.
Publicado: (2020)

Novel Regulatory Mechanisms of Pathogenicity and Virulence to Combat MDR in Candida albicans
por: Hameed, Saif, et al.
Publicado: (2013)

Metabolomic profiling for the identification of potential biomarkers involved in a laboratory azole resistance in Candida albicans
por: Li, Ling, et al.
Publicado: (2018)

Repurposing pantoprazole and haloperidol as efflux pump inhibitors in azole resistant clinical Candida albicans and non-albicans isolates
por: El-Ganiny, Amira M., et al.
Publicado: (2022)

ERG11 Gene Mutations and MDR1 Upregulation Confer Pan-Azole Resistance in Candida tropicalis Causing Disseminated Candidiasis in an Acute Lymphoblastic Leukemia Patient on Posaconazole Prophylaxis
por: You, Liangshun, et al.
Publicado: (2017)

Successful Treatment of Chronic Mucocutaneous Candidiasis Caused by Azole-Resistant Candida albicans with Posaconazole
por: Firinu, Davide, et al.
Publicado: (2011)

Structural design of microbicidal cationic oligomers and their synergistic interaction with azoles against Candida albicans
por: Yuan, Yuan, et al.
Publicado: (2019)

Molecular mechanism of azoles resistant Candida albicans in a patient with chronic mucocutaneous candidiasis
por: Zhang, Ming-rui, et al.
Publicado: (2020)

Synergistic Effects and Mechanisms of Combined Treatment With Harmine Hydrochloride and Azoles for Resistant Candida albicans
por: Li, Xiuyun, et al.
Publicado: (2019)

Catechol thwarts virulent dimorphism in Candida albicans and potentiates the antifungal efficacy of azoles and polyenes
por: Jothi, Ravi, et al.
Publicado: (2021)

Overexpression of MDR-1 and CDR-2 genes in fluconazole resistance of Candida albicans isolated from patients with vulvovaginal candidiasis
por: Khosravi Rad, K, et al.
Publicado: (2016)

Effect of Acetic Acid and Lactic Acid at Low pH in Growth and Azole Resistance of Candida albicans and Candida glabrata
por: Lourenço, Andreia, et al.
Publicado: (2019)

618. Fluconazole-Resistant Candida albicans Vaginitis with Cross-Resistance to Azoles: A Case Report
por: Akdağ, Damla, et al.
Publicado: (2019)

High incidence of azole resistance among Candida albicans and C. glabrata isolates in Northeastern Iran
por: Zarrinfar, Hossein, et al.
Publicado: (2021)

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans
por: Banerjee, Atanu, et al.
Publicado: (2021)

High frequency of azole resistant Candida spp. colonization among presumptive multidrug resistant tuberculosis (MDR-TB) patients
por: Darma, Surya, et al.
Publicado: (2020)

Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance
por: Kim, Sang Hu, et al.
Publicado: (2019)

Azole potentiation in Candida species
por: Stenkiewicz-Witeska, Jan S., et al.
Publicado: (2023)

Author Correction: Catechol thwarts virulent dimorphism in Candida albicans and potentiates the antifungal efficacy of azoles and polyenes
por: Jothi, Ravi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0s1nt1t4een2cgumc856ilvjiv