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Farnesyltransferase inhibitors prevent HIV protease inhibitor (lopinavir/ritonavir)-induced lipodystrophy and metabolic syndrome in mice

Highly active antiretroviral therapy (HAART) has successfully reduced the mortality rate of patients with human immune deficiency virus (HIV) and HIV protease inhibitors (HIV PIs) are key components of HAART. Complications of HAART, particularly those associated with HIV PIs including lipodystrophy...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomokazu, Nakazawa, Harumasa, Kuriyama, Naohide, Kaneki, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774418/
https://www.ncbi.nlm.nih.gov/pubmed/29434718
http://dx.doi.org/10.3892/etm.2017.5526

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