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AG490 ameliorates early brain injury via inhibition of JAK2/STAT3-mediated regulation of HMGB1 in subarachnoid hemorrhage

High mobility group box 1 (HMGB1) is a classic damage-associated molecular pattern that has an important role in the pathological inflammatory response. In vitro studies have demonstrated that the Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway is i...

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Detalles Bibliográficos
Autores principales:	An, Ji-Yang, Pang, Hong-Gang, Huang, Ting-Qin, Song, Jin-Ning, Li, Dan-Dong, Zhao, Yong-Lin, Ma, Xu-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774435/ https://www.ncbi.nlm.nih.gov/pubmed/29434719 http://dx.doi.org/10.3892/etm.2017.5539

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