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Autophagy activation promotes bevacizumab resistance in glioblastoma by suppressing Akt/mTOR signaling pathway

Glioblastomas are the most common primary and malignant brain tumors. The standard therapy includes surgery and radiotherapy plus chemotherapy, with additional bevacizumab to block the angiogenesis in tumors. However, the ever-growing tolerance of glioblastomas to chemotherapeutic drugs impairs the...

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Detalles Bibliográficos
Autores principales: Huang, He, Song, Jian, Liu, Zheng, Pan, Li, Xu, Guozheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774481/
https://www.ncbi.nlm.nih.gov/pubmed/29434840
http://dx.doi.org/10.3892/ol.2017.7446

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