Steroid-resistant nephrotic syndrome: past and current perspectives

Patients with steroid-resistant nephrotic syndrome (SRNS) represent a challenging subset of patients with nephrotic syndrome who often fail standard immunosuppression and have a higher likelihood of progressing to end-stage renal disease. Appropriate treatment of SRNS requires an adequate understand...

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Detalles Bibliográficos
Autores principales: Nourbakhsh, Noureddin, Mak, Robert H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774596/
https://www.ncbi.nlm.nih.gov/pubmed/29388620
http://dx.doi.org/10.2147/PHMT.S100803
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author Nourbakhsh, Noureddin
Mak, Robert H
author_facet Nourbakhsh, Noureddin
Mak, Robert H
author_sort Nourbakhsh, Noureddin
collection PubMed
description Patients with steroid-resistant nephrotic syndrome (SRNS) represent a challenging subset of patients with nephrotic syndrome who often fail standard immunosuppression and have a higher likelihood of progressing to end-stage renal disease. Appropriate treatment of SRNS requires an adequate understanding of the historical treatment, renal histopathology, and genetics associated with the disease. The aim of this review is to present a comprehensive appraisal of the history, role of renal biopsy, genetics, and treatment of SRNS.
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spelling pubmed-57745962018-01-31 Steroid-resistant nephrotic syndrome: past and current perspectives Nourbakhsh, Noureddin Mak, Robert H Pediatric Health Med Ther Review Patients with steroid-resistant nephrotic syndrome (SRNS) represent a challenging subset of patients with nephrotic syndrome who often fail standard immunosuppression and have a higher likelihood of progressing to end-stage renal disease. Appropriate treatment of SRNS requires an adequate understanding of the historical treatment, renal histopathology, and genetics associated with the disease. The aim of this review is to present a comprehensive appraisal of the history, role of renal biopsy, genetics, and treatment of SRNS. Dove Medical Press 2017-04-11 /pmc/articles/PMC5774596/ /pubmed/29388620 http://dx.doi.org/10.2147/PHMT.S100803 Text en © 2017 Nourbakhsh and Mak. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Nourbakhsh, Noureddin
Mak, Robert H
Steroid-resistant nephrotic syndrome: past and current perspectives
title Steroid-resistant nephrotic syndrome: past and current perspectives
title_full Steroid-resistant nephrotic syndrome: past and current perspectives
title_fullStr Steroid-resistant nephrotic syndrome: past and current perspectives
title_full_unstemmed Steroid-resistant nephrotic syndrome: past and current perspectives
title_short Steroid-resistant nephrotic syndrome: past and current perspectives
title_sort steroid-resistant nephrotic syndrome: past and current perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774596/
https://www.ncbi.nlm.nih.gov/pubmed/29388620
http://dx.doi.org/10.2147/PHMT.S100803
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