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Decreased MiR-17 in glioma cells increased cell viability and migration by increasing the expression of Cyclin D1, p-Akt and Akt
BACKGROUND: The activating mutations of micro RNA (miR)-17 have been revealed in tumors such as human non-Hodgkin's lymphoma and T cell leukemia. However, it is unclear about the role of miR-17 in glioma cells. The current study aimed to investigate effects of miR-17 mimics or inhibitor on the...
Autores principales: | Sun, Guangwei, SiMa, Guozhong, Wu, Chunhui, Fan, Yongzhong, Tan, Yong, Wang, Zhong, Cheng, Gang, Li, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774692/ https://www.ncbi.nlm.nih.gov/pubmed/29351283 http://dx.doi.org/10.1371/journal.pone.0190515 |
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