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Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh

Recent advances in statistical methods enable the study of correlation among outcomes through joint modeling, thereby addressing spillover effects. By joint modeling, we refer to simultaneously analyzing two or more different response variables emanating from the same individual. Using the 2011 Bang...

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Detalles Bibliográficos
Autores principales: Fang, Di, Sun, Renyuan, Wilson, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774700/
https://www.ncbi.nlm.nih.gov/pubmed/29351328
http://dx.doi.org/10.1371/journal.pone.0190917
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author Fang, Di
Sun, Renyuan
Wilson, Jeffrey R.
author_facet Fang, Di
Sun, Renyuan
Wilson, Jeffrey R.
author_sort Fang, Di
collection PubMed
description Recent advances in statistical methods enable the study of correlation among outcomes through joint modeling, thereby addressing spillover effects. By joint modeling, we refer to simultaneously analyzing two or more different response variables emanating from the same individual. Using the 2011 Bangladesh Demographic and Health Survey, we jointly address spillover effects between contraceptive use (CUC) and knowledge of HIV and other sexually transmitted diseases. Jointly modeling these two outcomes is appropriate because certain types of contraceptive use contribute to the prevention of HIV and STDs and the knowledge and awareness of HIV and STDs typically lead to protection during sexual intercourse. In particular, we compared the differences as they pertained to the interpretive advantage of modeling the spillover effects of joint modeling HIV and CUC as opposed to addressing them separately. We also identified risk factors that determine contraceptive use and knowledge of HIV and STDs among women in Bangladesh. We found that by jointly modeling the correlation between HIV knowledge and contraceptive use, the importance of education decreased. The HIV prevention program had a spillover effect on CUC: what seemed to be impacted by education can be partially contributed to one’s exposure to HIV knowledge. The joint model revealed a less significant impact of covariates as opposed to both separate models and standard models. Additionally, we found a spillover effect that would have otherwise been undiscovered if we did not jointly model. These findings further suggested that the simultaneous impact of correlated outcomes can be adequately addressed for the commonality between different responses and deflate, which is otherwise overestimated when examined separately.
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spelling pubmed-57747002018-01-26 Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh Fang, Di Sun, Renyuan Wilson, Jeffrey R. PLoS One Research Article Recent advances in statistical methods enable the study of correlation among outcomes through joint modeling, thereby addressing spillover effects. By joint modeling, we refer to simultaneously analyzing two or more different response variables emanating from the same individual. Using the 2011 Bangladesh Demographic and Health Survey, we jointly address spillover effects between contraceptive use (CUC) and knowledge of HIV and other sexually transmitted diseases. Jointly modeling these two outcomes is appropriate because certain types of contraceptive use contribute to the prevention of HIV and STDs and the knowledge and awareness of HIV and STDs typically lead to protection during sexual intercourse. In particular, we compared the differences as they pertained to the interpretive advantage of modeling the spillover effects of joint modeling HIV and CUC as opposed to addressing them separately. We also identified risk factors that determine contraceptive use and knowledge of HIV and STDs among women in Bangladesh. We found that by jointly modeling the correlation between HIV knowledge and contraceptive use, the importance of education decreased. The HIV prevention program had a spillover effect on CUC: what seemed to be impacted by education can be partially contributed to one’s exposure to HIV knowledge. The joint model revealed a less significant impact of covariates as opposed to both separate models and standard models. Additionally, we found a spillover effect that would have otherwise been undiscovered if we did not jointly model. These findings further suggested that the simultaneous impact of correlated outcomes can be adequately addressed for the commonality between different responses and deflate, which is otherwise overestimated when examined separately. Public Library of Science 2018-01-19 /pmc/articles/PMC5774700/ /pubmed/29351328 http://dx.doi.org/10.1371/journal.pone.0190917 Text en © 2018 Fang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Fang, Di
Sun, Renyuan
Wilson, Jeffrey R.
Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh
title Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh
title_full Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh
title_fullStr Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh
title_full_unstemmed Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh
title_short Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh
title_sort joint modeling of correlated binary outcomes: the case of contraceptive use and hiv knowledge in bangladesh
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774700/
https://www.ncbi.nlm.nih.gov/pubmed/29351328
http://dx.doi.org/10.1371/journal.pone.0190917
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