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Interactions of 2’-O-methyl oligoribonucleotides with the RNA models of the 30S subunit A-site
Synthetic oligonucleotides targeting functional regions of the prokaryotic rRNA could be promising antimicrobial agents. Indeed, such oligonucleotides were proven to inhibit bacterial growth. 2’-O-methylated (2’-O-Me) oligoribonucleotides with a sequence complementary to the decoding site in 16S rRN...
Autores principales: | Jasiński, Maciej, Kulik, Marta, Wojciechowska, Monika, Stolarski, Ryszard, Trylska, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774723/ https://www.ncbi.nlm.nih.gov/pubmed/29351348 http://dx.doi.org/10.1371/journal.pone.0191138 |
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