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5-aminosalicylic acid improves lipid profile in mice fed a high-fat cholesterol diet through its dual effects on intestinal PPARγ and PPARα

Obesity is associated with a series of metabolic complications, including dyslipidemia and insulin resistance (IR) that lack effective therapies. In recent years, intestinal inflammation has been suggested to contribute to obesity related metabolic syndrome and targeting gut inflammation with 5-ASA...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Koonen, Debby, Hofker, Marten, Bao, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774772/
https://www.ncbi.nlm.nih.gov/pubmed/29352300
http://dx.doi.org/10.1371/journal.pone.0191485