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Inhibition of interleukin-6 decreases atrogene expression and ameliorates tail suspension-induced skeletal muscle atrophy

BACKGROUND: Interleukin-6 (IL-6) is an inflammatory cytokine. Whether systemic IL-6 affects atrogene expression and disuse-induced skeletal muscle atrophy is unclear. METHODS: Tail-suspended mice were used as a disuse-induced muscle atrophy model. We administered anti-mouse IL-6 receptor antibody, b...

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Detalles Bibliográficos
Autores principales:	Yakabe, Mitsutaka, Ogawa, Sumito, Ota, Hidetaka, Iijima, Katsuya, Eto, Masato, Ouchi, Yasuyoshi, Akishita, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774788/ https://www.ncbi.nlm.nih.gov/pubmed/29351340 http://dx.doi.org/10.1371/journal.pone.0191318

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