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Inflammatory-linked changes in CpG island methylation of three opioid peptide genes in a rat model for pain
Expression of the opioid peptide genes proopiomelanocortin (Pomc), proenkephalin (Penk), and prodynorphin (Pdyn), in immune cells plays a key role in endogenous pain control. In a rat model of painful unilateral paw inflammation, we isolated cells from popliteal lymph nodes and evaluated the role of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774833/ https://www.ncbi.nlm.nih.gov/pubmed/29352321 http://dx.doi.org/10.1371/journal.pone.0191698 |