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Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators

Transposable elements (TEs) are now recognized not only as parasitic DNA, whose spread in the genome must be controlled by the host, but also as major players in genome evolution and regulation(1,2,3,4,5,6). Long INterspersed Element-1 (LINE-1 or L1), the only currently autonomous mobile transposon...

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Detalles Bibliográficos
Autores principales: Liu, Nian, Lee, Cameron H., Swigut, Tomek, Grow, Edward, Gu, Bo, Bassik, Michael, Wysocka, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774979/
https://www.ncbi.nlm.nih.gov/pubmed/29211708
http://dx.doi.org/10.1038/nature25179