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Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis

We present a 27-year-old lady with HIV-1 infection who died due to rapidly worsening respiratory failure one day after commencing amphotericin B deoxycholate therapy for cryptococcal meningitis. Chest x-ray appearances were consistent with pneumocystis pneumonia but post mortem examination showed ev...

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Autores principales: Scriven, James E., Botha, Francois CJ, Schutz, Charlotte, Lalloo, David G., Wainwright, Helen, Meintjes, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775074/
https://www.ncbi.nlm.nih.gov/pubmed/29379704
http://dx.doi.org/10.1016/j.mmcr.2017.02.004
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author Scriven, James E.
Botha, Francois CJ
Schutz, Charlotte
Lalloo, David G.
Wainwright, Helen
Meintjes, Graeme
author_facet Scriven, James E.
Botha, Francois CJ
Schutz, Charlotte
Lalloo, David G.
Wainwright, Helen
Meintjes, Graeme
author_sort Scriven, James E.
collection PubMed
description We present a 27-year-old lady with HIV-1 infection who died due to rapidly worsening respiratory failure one day after commencing amphotericin B deoxycholate therapy for cryptococcal meningitis. Chest x-ray appearances were consistent with pneumocystis pneumonia but post mortem examination showed evidence of severe necrotizing cryptococcal pneumonia. Cryptococcal pneumonia is an underrecognized condition and should be considered in the differential of patients with HIV-1 infection and low CD4 count who develop respiratory symptoms.
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spelling pubmed-57750742018-01-29 Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis Scriven, James E. Botha, Francois CJ Schutz, Charlotte Lalloo, David G. Wainwright, Helen Meintjes, Graeme Med Mycol Case Rep Special issue section Case Studies in AIDS related Mycoses; Edited by Tihana Bicanic and Darius Armstrong-James We present a 27-year-old lady with HIV-1 infection who died due to rapidly worsening respiratory failure one day after commencing amphotericin B deoxycholate therapy for cryptococcal meningitis. Chest x-ray appearances were consistent with pneumocystis pneumonia but post mortem examination showed evidence of severe necrotizing cryptococcal pneumonia. Cryptococcal pneumonia is an underrecognized condition and should be considered in the differential of patients with HIV-1 infection and low CD4 count who develop respiratory symptoms. Elsevier 2018-01-17 /pmc/articles/PMC5775074/ /pubmed/29379704 http://dx.doi.org/10.1016/j.mmcr.2017.02.004 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Special issue section Case Studies in AIDS related Mycoses; Edited by Tihana Bicanic and Darius Armstrong-James
Scriven, James E.
Botha, Francois CJ
Schutz, Charlotte
Lalloo, David G.
Wainwright, Helen
Meintjes, Graeme
Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis
title Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis
title_full Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis
title_fullStr Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis
title_full_unstemmed Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis
title_short Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis
title_sort paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin b treatment for hiv-associated cryptococcal meningitis
topic Special issue section Case Studies in AIDS related Mycoses; Edited by Tihana Bicanic and Darius Armstrong-James
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775074/
https://www.ncbi.nlm.nih.gov/pubmed/29379704
http://dx.doi.org/10.1016/j.mmcr.2017.02.004
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