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Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever

BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) is a fatal zoonotic viral disease caused by infection with a tick-borne virus of the genus Nairovirus. In this study, we investigated the incidence of brucellosis in patients diagnosed with CCHF. METHODS: Overall, 169 patients hospitalized with an i...

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Autores principales: Duygu, Fazilet, Sari, Tugba, Kaya, Turan, Bulut, Nermin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775153/
https://www.ncbi.nlm.nih.gov/pubmed/29367923
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author Duygu, Fazilet
Sari, Tugba
Kaya, Turan
Bulut, Nermin
author_facet Duygu, Fazilet
Sari, Tugba
Kaya, Turan
Bulut, Nermin
author_sort Duygu, Fazilet
collection PubMed
description BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) is a fatal zoonotic viral disease caused by infection with a tick-borne virus of the genus Nairovirus. In this study, we investigated the incidence of brucellosis in patients diagnosed with CCHF. METHODS: Overall, 169 patients hospitalized with an initial diagnosis of CCHF were included in 2011 in Tokat/Turkey. Immunoglobulin M (IgM) antibodies and/or PCR results were used in the laboratory diagnosis of CCHF, while plate and standard tube agglutination (STA) tests were used to diagnose brucellosis. RESULTS: Overall, 120 patients (79%) with positive PCR tests were diagnosed with CCHF. Five (4.16%) were also diagnosed with brucellosis based on the positive plate and STA test results. Four patients (2.36%) had negative CCHF PCR and positive STA test results. CONCLUSION: Brucellosis and CCHF can mimic each other and that all patients with CCHF or brucellosis should be screened for both conditions.
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spelling pubmed-57751532018-01-24 Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever Duygu, Fazilet Sari, Tugba Kaya, Turan Bulut, Nermin J Arthropod Borne Dis Original Article BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) is a fatal zoonotic viral disease caused by infection with a tick-borne virus of the genus Nairovirus. In this study, we investigated the incidence of brucellosis in patients diagnosed with CCHF. METHODS: Overall, 169 patients hospitalized with an initial diagnosis of CCHF were included in 2011 in Tokat/Turkey. Immunoglobulin M (IgM) antibodies and/or PCR results were used in the laboratory diagnosis of CCHF, while plate and standard tube agglutination (STA) tests were used to diagnose brucellosis. RESULTS: Overall, 120 patients (79%) with positive PCR tests were diagnosed with CCHF. Five (4.16%) were also diagnosed with brucellosis based on the positive plate and STA test results. Four patients (2.36%) had negative CCHF PCR and positive STA test results. CONCLUSION: Brucellosis and CCHF can mimic each other and that all patients with CCHF or brucellosis should be screened for both conditions. Tehran University of Medical Sciences 2017-12-30 /pmc/articles/PMC5775153/ /pubmed/29367923 Text en Copyright© Iranian Society of Medical Entomology & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Duygu, Fazilet
Sari, Tugba
Kaya, Turan
Bulut, Nermin
Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever
title Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever
title_full Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever
title_fullStr Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever
title_full_unstemmed Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever
title_short Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever
title_sort brucellosis in patients with crimean-congo hemorrhagic fever
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775153/
https://www.ncbi.nlm.nih.gov/pubmed/29367923
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