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Computational Study of PCSK9-EGFA Complex with Effective Polarizable Bond Force Field

Inhibiting of Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) binding is an effective way for reducing Low Density Lipoprotein cholesterol (LDL-C). Understanding the interaction between PCSK9 and LDLR is useful for PCSK9 inhibitor design. In this wor...

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Detalles Bibliográficos
Autores principales:	Chen, Jian, Duan, Lili, Ji, Changge, Zhang, John Z. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775225/ https://www.ncbi.nlm.nih.gov/pubmed/29379787 http://dx.doi.org/10.3389/fmolb.2017.00101

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