Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report

Human T-lymphotropic virus 1 (HTLV-1) infection has been associated with ATL and inflammatory diseases but remains a neglected health problem. HTLV-1 associated diseases were originally described as sporadic entities, but family aggregations have been reported. Viral, genetic, immunological and beha...

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Autores principales: Vallinoto, Antonio C. R., Santana, Bárbara B., Queiroz, Maria A. F., da Silva, Andrea N. M. R., Cayres-Vallinoto, Izaura M. V., da Costa, Carlos A., de Sousa, Maisa S., Ishak, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775226/
https://www.ncbi.nlm.nih.gov/pubmed/29379480
http://dx.doi.org/10.3389/fmicb.2017.02685
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author Vallinoto, Antonio C. R.
Santana, Bárbara B.
Queiroz, Maria A. F.
da Silva, Andrea N. M. R.
Cayres-Vallinoto, Izaura M. V.
da Costa, Carlos A.
de Sousa, Maisa S.
Ishak, Ricardo
author_facet Vallinoto, Antonio C. R.
Santana, Bárbara B.
Queiroz, Maria A. F.
da Silva, Andrea N. M. R.
Cayres-Vallinoto, Izaura M. V.
da Costa, Carlos A.
de Sousa, Maisa S.
Ishak, Ricardo
author_sort Vallinoto, Antonio C. R.
collection PubMed
description Human T-lymphotropic virus 1 (HTLV-1) infection has been associated with ATL and inflammatory diseases but remains a neglected health problem. HTLV-1 associated diseases were originally described as sporadic entities, but family aggregations have been reported. Viral, genetic, immunological and behavioral factors were used to explain family clusters, but until now a clear explanation remains uncertain. In the present study we report, for the first time, a family cluster of diseased persons presenting the infection across three generations associated with FAS -670A/G polymorphism.
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spelling pubmed-57752262018-01-29 Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report Vallinoto, Antonio C. R. Santana, Bárbara B. Queiroz, Maria A. F. da Silva, Andrea N. M. R. Cayres-Vallinoto, Izaura M. V. da Costa, Carlos A. de Sousa, Maisa S. Ishak, Ricardo Front Microbiol Microbiology Human T-lymphotropic virus 1 (HTLV-1) infection has been associated with ATL and inflammatory diseases but remains a neglected health problem. HTLV-1 associated diseases were originally described as sporadic entities, but family aggregations have been reported. Viral, genetic, immunological and behavioral factors were used to explain family clusters, but until now a clear explanation remains uncertain. In the present study we report, for the first time, a family cluster of diseased persons presenting the infection across three generations associated with FAS -670A/G polymorphism. Frontiers Media S.A. 2018-01-15 /pmc/articles/PMC5775226/ /pubmed/29379480 http://dx.doi.org/10.3389/fmicb.2017.02685 Text en Copyright © 2018 Vallinoto, Santana, Queiroz, da Silva, Cayres-Vallinoto, da Costa, de Sousa and Ishak. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Vallinoto, Antonio C. R.
Santana, Bárbara B.
Queiroz, Maria A. F.
da Silva, Andrea N. M. R.
Cayres-Vallinoto, Izaura M. V.
da Costa, Carlos A.
de Sousa, Maisa S.
Ishak, Ricardo
Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report
title Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report
title_full Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report
title_fullStr Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report
title_full_unstemmed Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report
title_short Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report
title_sort family aggregation of htlv-1 infection associated with fas -670a/g polymorphism: a case report
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775226/
https://www.ncbi.nlm.nih.gov/pubmed/29379480
http://dx.doi.org/10.3389/fmicb.2017.02685
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