Classic Ulcerative Pyoderma Gangrenosum Is a T Cell-Mediated Disease Targeting Follicular Adnexal Structures: A Hypothesis Based on Molecular and Clinicopathologic Studies

BACKGROUND: Pyoderma gangrenosum (PG) is a debilitating ulcerative skin disease that is one of the most common associated diseases seen in patients with inflammatory bowel disease and rheumatoid arthritis. Although PG is classified as a neutrophilic dermatosis, its pathophysiology is poorly understo...

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Detalles Bibliográficos
Autores principales: Wang, Elizabeth A., Steel, Andrea, Luxardi, Guillaume, Mitra, Anupam, Patel, Forum, Cheng, Michelle Y., Wilken, Reason, Kao, Jason, de Ga, Kristopher, Sultani, Hawa, Merleev, Alexander A., Marusina, Alina I., Brassard, Alain, Fung, Maxwell A., Konia, Thomas, Shimoda, Michiko, Maverakis, Emanual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775228/
https://www.ncbi.nlm.nih.gov/pubmed/29379508
http://dx.doi.org/10.3389/fimmu.2017.01980

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