Cargando…

AIMp1 Potentiates T(H)1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity

Dendritic cells (DCs) must integrate a broad array of environmental cues to exact control over downstream immune responses including T(H) polarization. The multienzyme aminoacyl-tRNA synthetase complex component AIMp1/p43 responds to cellular stress and exerts pro-inflammatory functions; however, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Dan, Tian, Lin, You, Ran, Halpert, Matthew M., Konduri, Vanaja, Baig, Yunyu C., Paust, Silke, Kim, Doyeun, Kim, Sunghoon, Jia, Fuli, Huang, Shixia, Zhang, Xiang, Kheradmand, Farrah, Corry, David B., Gilbert, Brian E., Levitt, Jonathan M., Decker, William K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775236/ https://www.ncbi.nlm.nih.gov/pubmed/29379495 http://dx.doi.org/10.3389/fimmu.2017.01801

Ejemplares similares

AIMP3 Deletion Induces Acute Radiation Syndrome-like Phenotype in Mice
por: Kim, Doyeun, et al.
Publicado: (2018)

AIMP3 depletion causes genome instability and loss of stemness in mouse embryonic stem cells
por: Kim, Sun Mi, et al.
Publicado: (2018)

HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy
por: Kim, Chul, et al.
Publicado: (2019)

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis
por: Kim, Dae Gyu, et al.
Publicado: (2022)

CD8(+)CD161(+) T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential
por: Konduri, Vanaja, et al.
Publicado: (2021)

Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2
por: Kim, Dae Gyu, et al.
Publicado: (2020)

VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2
por: Yun, Seung Pil, et al.
Publicado: (2017)

Data on optimization of expression and purification of AIMP2-DX2 protein in Escherichia coli
por: Jha, Roshan, et al.
Publicado: (2017)

The DRS–AIMP2–EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex
por: Hahn, Hyunggu, et al.
Publicado: (2019)

Degradation of AIMP1/p43 Induced by Hepatitis C Virus E2 Leads to Upregulation of TGF-β Signaling and Increase in Surface Expression of gp96
por: Kim, Min Soo, et al.
Publicado: (2014)

Single-cell analysis of AIMP2 splice variants informs on drug sensitivity and prognosis in hematologic cancer
por: Ku, Jayoung, et al.
Publicado: (2020)

Mapping the contact surfaces in the Lamin A:AIMP3 complex by hydrogen/deuterium exchange FT-ICR mass spectrometry
por: Tao, Yeqing, et al.
Publicado: (2017)

An Isoform of the Oncogenic Splice Variant AIMP2-DX2 Detected by a Novel Monoclonal Antibody
por: Kim, Dae Gyu, et al.
Publicado: (2020)

Ratio of Autoantibodies of Tumor Suppressor AIMP2 and Its Oncogenic Variant Is Associated with Clinical Outcome in Lung Cancer
por: Jung, Ji Ye, et al.
Publicado: (2017)

Cancer Immunotherapy: Historical Perspective of a Clinical Revolution and Emerging Preclinical Animal Models
por: Decker, William K., et al.
Publicado: (2017)

Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug
por: Lee, BoRa, et al.
Publicado: (2022)

Cancer-Associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis
por: Choi, Jin Woo, et al.
Publicado: (2011)

Beyond T-Cells: Functional Characterization of CTLA-4 Expression in Immune and Non-Immune Cell Types
por: Oyewole-Said, Damilola, et al.
Publicado: (2020)

Functional Fragments of AIMP1-Derived Peptide (AdP) and Optimized Hydrosol for Their Topical Deposition by Box-Behnken Design
por: Lee, Jeong-Jun, et al.
Publicado: (2019)

AIMP3 inhibits cell growth and metastasis of lung adenocarcinoma through activating a miR‐96‐5p‐AIMP3‐p53 axis
por: Ding, Liting, et al.
Publicado: (2021)

Parthanatos Mediates AIMP2 Activated Age Dependent Dopaminergic Neuronal Loss
por: Lee, Yunjong, et al.
Publicado: (2013)

Environmental contributions to the allergic asthma epidemic.
por: Kheradmand, Farrah, et al.
Publicado: (2002)

Divergent Mast Cell Responses Modulate Antiviral Immunity During Influenza Virus Infection
por: Murphy-Schafer, Ashleigh R., et al.
Publicado: (2021)

AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal
por: Ahn, J, et al.
Publicado: (2016)

Rare Neurologic Disease-Associated Mutations of AIMP1 Are Related with Inhibitory Neuronal Differentiation Which Is Reversed by Ibuprofen
por: Takeuchi, Yu, et al.
Publicado: (2020)

AIMP2-DX2 Promotes the Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma Cells
por: Cao, Qingsong, et al.
Publicado: (2018)

AIMP1 Mutation Long-Term Follow-Up, With Decreased Brain N-Acetylaspartic Acid and Secondary Mitochondrial Abnormalities
por: Khan, Aneal, et al.
Publicado: (2019)

Fluorescence-Based Analysis of Noncanonical Functions of Aminoacyl-tRNA Synthetase-Interacting Multifunctional Proteins (AIMPs) in Peripheral Nerves
por: Kim, Muwoong, et al.
Publicado: (2019)

Alveolar macrophages in lung cancer: opportunities and challenges
por: Chang, Cheng-Yen, et al.
Publicado: (2023)

Corrigendum: Alveolar macrophages in lung cancer: opportunities and challenges
por: Chang, Cheng-Yen, et al.
Publicado: (2023)

Humanized Mice for the Evaluation of Novel HIV-1 Therapies
por: Abeynaike, Shawn, et al.
Publicado: (2021)

Corrigendum: Humanized Mice for the Evaluation of Novel HIV-1 Therapies
por: Abeynaike, Shawn, et al.
Publicado: (2021)

Dendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma
por: Konduri, V., et al.
Publicado: (2019)

AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation
por: Wei, Rongfang, et al.
Publicado: (2022)

Structural basis of AimP signaling molecule recognition by AimR in Spbeta group of bacteriophages
por: Zhen, Xiangkai, et al.
Publicado: (2018)

Lung Cancer Heterogeneity in Modulation of Th17/IL17A Responses
por: Armstrong, Dominique, et al.
Publicado: (2019)

Natural killer cells and cytotoxic T lymphocytes are required to clear solid tumor in a patient-derived xenograft
por: Le, Duy Tri, et al.
Publicado: (2021)

Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2
por: Zheng, Yilin, et al.
Publicado: (2023)

Meta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumors
por: Chen, Fengju, et al.
Publicado: (2021)

Airway Mycosis and the Regulation of Type 2 Immunity
por: Knight, John Morgan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_v40idf0tqi6r8iple01fbo4d6e