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Reduction in hepatic secondary bile acids caused by short-term antibiotic-induced dysbiosis decreases mouse serum glucose and triglyceride levels

Antibiotic-caused changes in intestinal flora (dysbiosis) can have various effects on the host. Secondary bile acids produced by intestinal bacteria are ligands for specific nuclear receptors, which regulate glucose, lipid, and drug metabolism in the liver. The present study aimed to clarify the eff...

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Detalles Bibliográficos
Autores principales: Kuno, Takuya, Hirayama-Kurogi, Mio, Ito, Shingo, Ohtsuki, Sumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775293/
https://www.ncbi.nlm.nih.gov/pubmed/29352187
http://dx.doi.org/10.1038/s41598-018-19545-1

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