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Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia

MicroRNAs (miRNAs) have been suggested to repress transcription via binding the 3′-untranslated regions of mRNAs. However, the involvement and details of miRNA-mediated epigenetic regulation, particularly in targeting genomic DNA and mediating epigenetic regulation, remain largely uninvestigated. In...

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Detalles Bibliográficos
Autores principales:	Chu, Yu-Yi, Ko, Chiung-Yuan, Wang, Shao-Ming, Lin, Pin-I, Wang, Han-Ying, Lin, Wen-Chi, Wu, Dong-Yu, Wang, Lu-Hao, Wang, Ju-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775404/ https://www.ncbi.nlm.nih.gov/pubmed/29120412 http://dx.doi.org/10.1038/cddis.2017.520

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