Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is characterized by extremely poor prognosis. The standard chemotherapeutic drug, gemcitabine, does not offer significant improvements for PDAC management due to the rapid acquisition of drug resistance by patients. Recent evidence indicates that epithelial-to...

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Detalles Bibliográficos
Autores principales: Passacantilli, Ilaria, Panzeri, Valentina, Bielli, Pamela, Farini, Donatella, Pilozzi, Emanuela, Fave, Gianfranco Delle, Capurso, Gabriele, Sette, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775412/
https://www.ncbi.nlm.nih.gov/pubmed/29120411
http://dx.doi.org/10.1038/cddis.2017.562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775412/
https://www.ncbi.nlm.nih.gov/pubmed/29120411
http://dx.doi.org/10.1038/cddis.2017.562

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