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Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K(+) channel Kv1.5
The voltage-gated K(+) channel has key roles in the vasculature and in atrial excitability and contributes to apoptosis in various tissues. In this study, we have explored its regulation by carbon monoxide (CO), a product of the cytoprotective heme oxygenase enzymes, and a recognized toxin. CO inhib...
Autores principales: | Al-Owais, Moza M, Hettiarachchi, Nishani T, Boyle, John P, Scragg, Jason L, Elies, Jacobo, Dallas, Mark L, Lippiat, Jon D, Steele, Derek S, Peers, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775415/ https://www.ncbi.nlm.nih.gov/pubmed/29095440 http://dx.doi.org/10.1038/cddis.2017.568 |
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