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oriD structure controls RepD initiation during rolling-circle replication

Bacterial antibiotic resistance is often carried by circular DNA plasmids that are copied separately from the genomic DNA and can be passed to other bacteria, spreading the resistance. The chloramphenicol-resistance plasmid pC221 from Staphylococcus aureus is duplicated by a process called asymmetri...

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Detalles Bibliográficos
Autores principales: Toleikis, Algirdas, Webb, Martin R., Molloy, Justin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775427/
https://www.ncbi.nlm.nih.gov/pubmed/29352198
http://dx.doi.org/10.1038/s41598-017-18817-6