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Are minor alleles more likely to be risk alleles?

BACKGROUND: Genome-wide association studies (GWASs) have revealed relationships between over 57,000 genetic variants and diseases. However, unlike Mendelian diseases, complex diseases arise from the interplay of multiple genetic and environmental factors. Natural selection has led to a high tendency...

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Detalles Bibliográficos
Autores principales:	Kido, Takashi, Sikora-Wohlfeld, Weronika, Kawashima, Minae, Kikuchi, Shinichi, Kamatani, Naoyuki, Patwardhan, Anil, Chen, Richard, Sirota, Marina, Kodama, Keiichi, Hadley, Dexter, Butte, Atul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775585/ https://www.ncbi.nlm.nih.gov/pubmed/29351777 http://dx.doi.org/10.1186/s12920-018-0322-5

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