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Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo

BACKGROUND: The diagnosis of hypertension in children is complex because based on normative values by sex, age and height, and these values vary depending on the environment. Available BP references used, because of the absence of local data, do not correspond to our pediatric population. Accordingl...

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Autores principales: Muyumba, Emmanuel Kiyana, Nkulu, Dophra Ngoy, Mukeng, Clarence Kaut, Musung, Jacques Mbaz, Kakoma, Placide Kambola, Kakisingi, Christian Ngama, Luboya, Oscar Numbi, Malonga, Françoise Kaj, Kizonde, Justin Kalungwe, Mukuku, Olivier, Yan, Weili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775618/
https://www.ncbi.nlm.nih.gov/pubmed/29351738
http://dx.doi.org/10.1186/s12872-018-0741-4
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author Muyumba, Emmanuel Kiyana
Nkulu, Dophra Ngoy
Mukeng, Clarence Kaut
Musung, Jacques Mbaz
Kakoma, Placide Kambola
Kakisingi, Christian Ngama
Luboya, Oscar Numbi
Malonga, Françoise Kaj
Kizonde, Justin Kalungwe
Mukuku, Olivier
Yan, Weili
author_facet Muyumba, Emmanuel Kiyana
Nkulu, Dophra Ngoy
Mukeng, Clarence Kaut
Musung, Jacques Mbaz
Kakoma, Placide Kambola
Kakisingi, Christian Ngama
Luboya, Oscar Numbi
Malonga, Françoise Kaj
Kizonde, Justin Kalungwe
Mukuku, Olivier
Yan, Weili
author_sort Muyumba, Emmanuel Kiyana
collection PubMed
description BACKGROUND: The diagnosis of hypertension in children is complex because based on normative values by sex, age and height, and these values vary depending on the environment. Available BP references used, because of the absence of local data, do not correspond to our pediatric population. Accordingly, our study aimed to provide the BP threshold for children and adolescents in Lubumbashi (DRC) and to compare them with German (KIGGS study), Polish (OLAF study) and Chinese (CHNS study) references. METHODS: We conducted a cross-sectional study among 7523 school-children aged 3 to 17 years. The standardized BP measurements were obtained using a validated oscillometric device (Datascope Accutor Plus). After excluding overweight and obese subjects according to the IOTF definition (n = 640), gender-specific SBP and DBP percentiles, which simultaneously accounted for age and height by using an extension of the LMS method, namely GAMLSS, were tabulated. RESULTS: The 50th, 90th and 95th percentiles of SBP and DBP for 3373 boys and 3510 girls were tabulated simultaneously by age and height (5th, 25th, 50th, 75th and 95th height percentile). Before 13 years the 50th and 90th percentiles of SBP for boys were higher compared with those of KIGGS and OLAF, and after they became lower: the difference for adolescents aged 17 years was respectively 8 mmHg (KIGGS) and 4 mmHg (OLAF). Concerning girls, the SBP 50th percentile was close to that of OLAF and KIGGS studies with differences that did not exceed 3 mmHg; whereas the 90th percentile of girls at different ages was high. Our oscillometric 50th and 90th percentiles of SBP and DBP were very high compared to referential ausculatory percentiles of the CHNS study respectively for boys from 8 to 14 mmHg and 7 to 13 mmHg; and for girls from 10 to 16 mmHg and 11 to 16 mmHg. CONCLUSIONS: The proposed BP thresholds percentiles enable early detection and treatment of children and adolescents with high BP and develop a local program of health promotion in schools and family. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12872-018-0741-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-57756182018-01-31 Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo Muyumba, Emmanuel Kiyana Nkulu, Dophra Ngoy Mukeng, Clarence Kaut Musung, Jacques Mbaz Kakoma, Placide Kambola Kakisingi, Christian Ngama Luboya, Oscar Numbi Malonga, Françoise Kaj Kizonde, Justin Kalungwe Mukuku, Olivier Yan, Weili BMC Cardiovasc Disord Research Article BACKGROUND: The diagnosis of hypertension in children is complex because based on normative values by sex, age and height, and these values vary depending on the environment. Available BP references used, because of the absence of local data, do not correspond to our pediatric population. Accordingly, our study aimed to provide the BP threshold for children and adolescents in Lubumbashi (DRC) and to compare them with German (KIGGS study), Polish (OLAF study) and Chinese (CHNS study) references. METHODS: We conducted a cross-sectional study among 7523 school-children aged 3 to 17 years. The standardized BP measurements were obtained using a validated oscillometric device (Datascope Accutor Plus). After excluding overweight and obese subjects according to the IOTF definition (n = 640), gender-specific SBP and DBP percentiles, which simultaneously accounted for age and height by using an extension of the LMS method, namely GAMLSS, were tabulated. RESULTS: The 50th, 90th and 95th percentiles of SBP and DBP for 3373 boys and 3510 girls were tabulated simultaneously by age and height (5th, 25th, 50th, 75th and 95th height percentile). Before 13 years the 50th and 90th percentiles of SBP for boys were higher compared with those of KIGGS and OLAF, and after they became lower: the difference for adolescents aged 17 years was respectively 8 mmHg (KIGGS) and 4 mmHg (OLAF). Concerning girls, the SBP 50th percentile was close to that of OLAF and KIGGS studies with differences that did not exceed 3 mmHg; whereas the 90th percentile of girls at different ages was high. Our oscillometric 50th and 90th percentiles of SBP and DBP were very high compared to referential ausculatory percentiles of the CHNS study respectively for boys from 8 to 14 mmHg and 7 to 13 mmHg; and for girls from 10 to 16 mmHg and 11 to 16 mmHg. CONCLUSIONS: The proposed BP thresholds percentiles enable early detection and treatment of children and adolescents with high BP and develop a local program of health promotion in schools and family. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12872-018-0741-4) contains supplementary material, which is available to authorized users. BioMed Central 2018-01-19 /pmc/articles/PMC5775618/ /pubmed/29351738 http://dx.doi.org/10.1186/s12872-018-0741-4 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Muyumba, Emmanuel Kiyana
Nkulu, Dophra Ngoy
Mukeng, Clarence Kaut
Musung, Jacques Mbaz
Kakoma, Placide Kambola
Kakisingi, Christian Ngama
Luboya, Oscar Numbi
Malonga, Françoise Kaj
Kizonde, Justin Kalungwe
Mukuku, Olivier
Yan, Weili
Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo
title Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo
title_full Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo
title_fullStr Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo
title_full_unstemmed Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo
title_short Oscillometric blood pressure by age and height for non overweight children and adolescents in Lubumbashi, Democratic Republic of Congo
title_sort oscillometric blood pressure by age and height for non overweight children and adolescents in lubumbashi, democratic republic of congo
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775618/
https://www.ncbi.nlm.nih.gov/pubmed/29351738
http://dx.doi.org/10.1186/s12872-018-0741-4
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