Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N-Acetylcysteine (NAC) and N-Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation

BACKGROUND: No new therapies for traumatic brain injury (TBI) have been officially translated into current practice. At the tissue and cellular level, both inflammatory and oxidative processes may be exacerbated post-injury and contribute to further brain damage. N-acetylcysteine (NAC) has the poten...

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Detalles Bibliográficos
Autores principales: Bhatti, Junaid, Nascimento, Barto, Akhtar, Umbreen, Rhind, Shawn G., Tien, Homer, Nathens, Avery, da Luz, Luis Teodoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776005/
https://www.ncbi.nlm.nih.gov/pubmed/29387038
http://dx.doi.org/10.3389/fneur.2017.00744

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