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Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length

A set of lipopeptides was recently reported for their broad-spectrum antiviral activity against viruses belonging to the Paramyxoviridae family, including human parainfluenza virus type 3 and Nipah virus. Among them, the peptide with a 24-unit PEG linker connecting it to a cholesterol moiety (VG-PEG...

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Detalles Bibliográficos
Autores principales: Augusto, Marcelo T., Hollmann, Axel, Porotto, Matteo, Moscona, Anne, Santos, Nuno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776016/
https://www.ncbi.nlm.nih.gov/pubmed/28714870
http://dx.doi.org/10.3390/molecules22071190