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Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis
Lymph nodes (LNs) are at the center of adaptive immune responses. Various exogenous substances are transported into LNs and a series of immune responses ensue after recognition by antigen–specific lymphocytes. Although humanized mice have been used to reconstitute the human immune system, most lack...
Autores principales: | Takahashi, Takeshi, Katano, Ikumi, Ito, Ryoji, Goto, Motohito, Abe, Hayato, Mizuno, Seiya, Kawai, Kenji, Sugiyama, Fumihiro, Ito, Mamoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776085/ https://www.ncbi.nlm.nih.gov/pubmed/29387068 http://dx.doi.org/10.3389/fimmu.2017.02017 |
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