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Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain

Neuronal metal ions such as zinc are essential for brain function. In particular synaptic processes are tightly related to metal and protein homeostasis, for example through extracellular metal-binding proteins. One such protein is neuronal S100B, a calcium and zinc binding damage-associated molecul...

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Detalles Bibliográficos
Autores principales: Hagmeyer, Simone, Cristóvão, Joana S., Mulvihill, John J. E., Boeckers, Tobias M., Gomes, Cláudio M., Grabrucker, Andreas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776125/
https://www.ncbi.nlm.nih.gov/pubmed/29386995
http://dx.doi.org/10.3389/fnmol.2017.00456