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[(18)F]-THK5351 PET Correlates with Topology and Symptom Severity in Progressive Supranuclear Palsy

Progressive supranuclear palsy (PSP) is a neurodegenerative movement disorder characterized by deposition of fibrillar aggregates of 4R tau-protein in neurons and glial cells of the brain. These deposits are a key neuropathological finding, allowing a diagnosis of “definite PSP,” which is usually es...

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Detalles Bibliográficos
Autores principales: Brendel, Matthias, Schönecker, Sonja, Höglinger, Günter, Lindner, Simon, Havla, Joachim, Blautzik, Janusch, Sauerbeck, Julia, Rohrer, Guido, Zach, Christian, Vettermann, Franziska, Lang, Anthony E., Golbe, Lawrence, Nübling, Georg, Bartenstein, Peter, Furukawa, Katsutoshi, Ishiki, Aiko, Bötzel, Kai, Danek, Adrian, Okamura, Nobuyuki, Levin, Johannes, Rominger, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776329/
https://www.ncbi.nlm.nih.gov/pubmed/29387005
http://dx.doi.org/10.3389/fnagi.2017.00440