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Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells

Allograft rejection is an important issue post cardiac transplantation. In order to investigate the effect of combined treatment with simvastatin and rapamycin on allograft rejection, a cardiac transplantation rat model was employed in the present study. The survival time of rats following cardiac t...

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Detalles Bibliográficos
Autores principales: Liu, Yingjie, Sun, Lu, Chen, Wei, Chuai, Junbo, Shang, Yu, Zhang, Dongyang, Fu, Bicheng, Tian, Hai, Jiang, Shulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776515/
https://www.ncbi.nlm.nih.gov/pubmed/29434788
http://dx.doi.org/10.3892/etm.2017.5635

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