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Extracellular Lactate: A Novel Measure of T Cell Proliferation

Following activation, T cells rapidly divide and acquire effector functions. This energetically demanding process depends upon the ability of T cells to undergo metabolic remodeling from oxidative phosphorylation to aerobic glycolysis, during which glucose is converted into lactate and released extr...

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Detalles Bibliográficos
Autores principales: Grist, James T., Jarvis, Lorna B., Georgieva, Zoya, Thompson, Sara, Kaur Sandhu, Harpreet, Burling, Keith, Clarke, Ashley, Jackson, Sarah, Wills, Mark, Gallagher, Ferdia A., Jones, Joanne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776880/
https://www.ncbi.nlm.nih.gov/pubmed/29288205
http://dx.doi.org/10.4049/jimmunol.1700886