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Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells

The development of anti-factor VIII antibodies is a major complication of the treatment of patients with hemophilia A. Generation of high affinity anti-factor VIII antibodies is dependent on help provided by CD4(+) T cells that recognize factor VIII-derived peptides presented on class II major histo...

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Detalles Bibliográficos
Autores principales: Peyron, Ivan, Hartholt, Robin B., Pedró-Cos, Laura, van Alphen, Floris, Brinke, Anja ten, Lardy, Neubury, Meijer, Alexander B., Voorberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777204/
https://www.ncbi.nlm.nih.gov/pubmed/29025906
http://dx.doi.org/10.3324/haematol.2017.175083