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Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells
The development of anti-factor VIII antibodies is a major complication of the treatment of patients with hemophilia A. Generation of high affinity anti-factor VIII antibodies is dependent on help provided by CD4(+) T cells that recognize factor VIII-derived peptides presented on class II major histo...
Autores principales: | Peyron, Ivan, Hartholt, Robin B., Pedró-Cos, Laura, van Alphen, Floris, Brinke, Anja ten, Lardy, Neubury, Meijer, Alexander B., Voorberg, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777204/ https://www.ncbi.nlm.nih.gov/pubmed/29025906 http://dx.doi.org/10.3324/haematol.2017.175083 |
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