Commensal bacteria produce GPCR ligands that mimic human signaling molecules

Commensal bacteria are believed to play important roles in human health. The mechanisms by which they affect mammalian physiology are poorly understood; however, bacterial metabolites are likely to be key components of host interactions. Here, we use bioinformatics and synthetic biology to mine the...

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Detalles Bibliográficos
Autores principales: Cohen, Louis J., Esterhazy, Daria, Kim, Seong-Hwan, Lemetre, Christophe, Aguilar, Rhiannon R., Gordon, Emma A., Pickard, Amanda J., Cross, Justin R., Emiliano, Ana B., Han, Sun M., Chu, John, Vila-Farres, Xavier, Kaplitt, Jeremy, Rogoz, Aneta, Calle, Paula Y., Hunter, Craig, Bitok, J. Kipchirchir, Brady, Sean F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777231/
https://www.ncbi.nlm.nih.gov/pubmed/28854168
http://dx.doi.org/10.1038/nature23874

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