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Molecular mimicking of C-terminal phosphorylation tunes the surface dynamics of Ca(V)1.2 calcium channels in hippocampal neurons
L-type voltage-gated Ca(V)1.2 calcium channels (Ca(V)1.2) are key regulators of neuronal excitability, synaptic plasticity, and excitation-transcription coupling. Surface-exposed Ca(V)1.2 distributes in clusters along the dendrites of hippocampal neurons. A permanent exchange between stably clustere...
Autores principales: | Folci, Alessandra, Steinberger, Angela, Lee, Boram, Stanika, Ruslan, Scheruebel, Susanne, Campiglio, Marta, Ramprecht, Claudia, Pelzmann, Brigitte, Hell, Johannes W., Obermair, Gerald J., Heine, Martin, Di Biase, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777246/ https://www.ncbi.nlm.nih.gov/pubmed/29180451 http://dx.doi.org/10.1074/jbc.M117.799585 |
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