Polarized macrophage subsets differentially express the drug efflux transporters MRP1 and BCRP, resulting in altered HIV production

INTRODUCTION: Macrophages play an important role in HIV, where they are a cellular reservoir. Macrophages are polarized into two phenotypes: pro-inflammatory M1 macrophages and anti-inflammatory M2 macrophages, which may have altered expression of drug efflux transporters, including BCRP and MRP1. T...

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Detalles Bibliográficos
Autores principales: He, Hui, Buckley, Merrion, Britton, Bernard, Mu, Ying, Warner, Kristin, Kumar, Santosh, Cory, Theodore J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777552/
https://www.ncbi.nlm.nih.gov/pubmed/29343083
http://dx.doi.org/10.1177/2040206617745168

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