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CryoEM structures of the human INO80 chromatin remodelling complex

Access to chromatin for processes such as DNA repair and transcription requires the sliding of nucleosomes along DNA. The multi-subunit INO80 chromatin remodelling complex has a particular role in DNA repair. Here we present the cryo electron microscopy structures of the active core complex of human...

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Detalles Bibliográficos
Autores principales: Aramayo, Ricardo J., Willhoft, Oliver, Ayala, Rafael, Bythell-Douglas, Rohan, Wigley, Dale B., Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777635/
https://www.ncbi.nlm.nih.gov/pubmed/29323271
http://dx.doi.org/10.1038/s41594-017-0003-7