Cargando…
Sodium fluoride induces apoptosis in mouse splenocytes by activating ROS-dependent NF-κB signaling
In this study, we investigated the roles of reactive oxygen species (ROS) and nuclear factor-κB (NF-κB) signaling in sodium fluoride-induced DNA damage and apoptosis in mouse splenocytes. Intragastric administration of 12, 24 or 48 mg/kg sodium fluoride resulted in a time- and dose-dependent increas...
Autores principales: | Deng, Huidan, Kuang, Ping, Cui, Hengmin, Luo, Qin, Liu, Huan, Lu, Yujiao, Fang, Jing, Zuo, Zhicai, Deng, Junliang, Li, Yinglun, Wang, Xun, Zhao, Ling |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777703/ https://www.ncbi.nlm.nih.gov/pubmed/29383091 http://dx.doi.org/10.18632/oncotarget.22826 |
Ejemplares similares
-
Sodium fluoride induces splenocyte autophagy via the mammalian targets of rapamycin (mTOR) signaling pathway in growing mice
por: Kuang, Ping, et al.
Publicado: (2018) -
Sodium fluoride induces renal inflammatory responses by activating NF-κB signaling pathway and reducing anti-inflammatory cytokine expression in mice
por: Luo, Qin, et al.
Publicado: (2017) -
Sodium fluoride causes oxidative stress and apoptosis in the mouse liver
por: Lu, Yujiao, et al.
Publicado: (2017) -
Effects of sodium fluoride on blood cellular and humoral immunity in mice
por: Guo, Hongrui, et al.
Publicado: (2017) -
Sodium fluoride causes hepatocellular S-phase arrest by activating ATM-p53-p21 and ATR-Chk1-Cdc25A pathways in mice
por: Liu, Huan, et al.
Publicado: (2017)