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SIRT1 regulates Mxd1 during malignant melanoma progression

In a murine melanoma model, malignant transformation promoted by a sustained stress condition was causally related to increased levels of reactive oxygen species resulting in DNA damage and massive epigenetic alterations. Since the chromatin modifier Sirtuin-1 (SIRT1) is a protein attracted to doubl...

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Detalles Bibliográficos
Autores principales:	Meliso, Fabiana M., Micali, Danilo, Silva, Camila T., Sabedot, Thaís S., Coetzee, Simon G., Koch, Adrian, Fahlbusch, Fabian B., Noushmehr, Houtan, Schneider-Stock, Regine, Jasiulionis, Miriam G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777712/ https://www.ncbi.nlm.nih.gov/pubmed/29383100 http://dx.doi.org/10.18632/oncotarget.21457

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