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Genetic variation in the NEIL2 DNA glycosylase gene is associated with oxidative DNA damage in BRCA2 mutation carriers
In this report, we have tried to gain molecular insight into a single nucleotide polymorphism (SNP) in the NEIL2 gene previously identified as “cancer risk modifier” for BRCA2 mutation carriers. To that end, we studied the role of this SNP (rs804271) on NEIL2 transcriptional regulation, oxidative DN...
Autores principales: | Benítez-Buelga, Carlos, Baquero, Juan Miguel, Vaclova, Tereza, Fernández, Victoria, Martín, Paloma, Inglada-Perez, Lucia, Urioste, Miguel, Osorio, Ana, Benítez, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777719/ https://www.ncbi.nlm.nih.gov/pubmed/29383107 http://dx.doi.org/10.18632/oncotarget.22638 |
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