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Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma

HSP70 connects multiple signaling pathways that work synergistically to protect tumor cells from death by proteotoxic stress and represents a possible target to establish a new approach for multiple myeloma treatment. Therefore, bioluminescent cell lines RPMI8226-LUC-PURO and U266-LUC-PURO were trea...

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Detalles Bibliográficos
Autores principales: Eugênio, Angela Isabel Pereira, Fook-Alves, Veruska Lia, de Oliveira, Mariana Bleker, Fernando, Rodrigo Carlini, Zanatta, Daniela B., Strauss, Bryan Eric, Silva, Maria Regina Regis, Porcionatto, Marimélia Aparecida, Colleoni, Gisele Wally Braga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777725/
https://www.ncbi.nlm.nih.gov/pubmed/29383113
http://dx.doi.org/10.18632/oncotarget.22815