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Pir-B inhibits the DC function and disturbs the Th17/Treg balance in lung cancer murine model

Paired immunoglobulin-like receptor B (Pir-B) was an inhibitory receptor expressed on the surfaces of dendritic cells (DCs). Pir-B inhibit T helper (Th) 1 response and induce Th2 cell differentiation, leading to the imbalance of Th1/Th2 cells. However, the role and potential mechanism of Pir-B on th...

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Detalles Bibliográficos
Autores principales: Wu, Huaxing, Zheng, Xiaoyu, Dong, Linlin, Li, Chunfeng, Zhang, Mingyue, Wang, Guonian, Wang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777726/
https://www.ncbi.nlm.nih.gov/pubmed/29383114
http://dx.doi.org/10.18632/oncotarget.21763