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CKS protein overexpression renders tumors susceptible to a chemotherapeutic strategy that protects normal tissues
The cyclin-dependent kinase-interacting proteins Cyclin-dependent Kinase Subunit 1 and 2 (CKS1 and 2) are frequently overexpressed in cancer and linked to increased aggressiveness and poor prognoses. We previously showed that CKS protein overexpression overrides the replication stress checkpoint act...
Autores principales: | Tat, John, Loriot, Céline, Henze, Martha, Spruck, Charles, Felding, Brunhilde H., Reed, Steven I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777741/ https://www.ncbi.nlm.nih.gov/pubmed/29383129 http://dx.doi.org/10.18632/oncotarget.22931 |
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