GSK-3β inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents

The complexities of GSK-3β function and interactions with PI3K/AKT/mTOR signaling, cell cycling, and apoptotic pathways are poorly understood in the context of lymphomagenesis and cancer therapeutics. In this study, we explored the anti-tumor effects of the GSK-3β inhibitor, 9-ING-41, in lymphoma ce...

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Detalles Bibliográficos
Autores principales: Karmali, Reem, Chukkapalli, Vineela, Gordon, Leo I., Borgia, Jeffrey A., Ugolkov, Andrey, Mazar, Andrew P., Giles, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777742/
https://www.ncbi.nlm.nih.gov/pubmed/29383130
http://dx.doi.org/10.18632/oncotarget.22414

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